Chromosome 14 - Alzheimer Disease


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Biology Chromosome 14 contains the maker for Alzheimer disease. Alzheimer disease is the fourth leading cause of death in adults, and the likelihood of getting it increases with age. Observed symptoms: progressive inability to remember facts and events and, later, to recognize friends and family. Mutation on chromosomes 1, 14, 19, and 21 are believed to play a role. Alzheimer runs in the family. A mutation is PS1 (or AD3) on chromosome 14. Fragments brain around amyloid-family proteins – somewhat similar to Down Syndrome Research in mice identified an enzyme that may be responsible for the increase in amyloid production characteristic of AD. If a way to regulate this enzyme could be found, then AD may be slowed or halted in some people.